The Center for Cancer Systems Pharmacology (CCSP) studies responsiveness and resistance to anti-cancer drugs.

How can we identify patients who will benefit from specific anti-cancer medicines and how can side-effects be minimized? Why do only some tumors respond to drugs, and why do those that do respond frequently become drug resistant? How should the choice between chemotherapy, targeted therapy and immunotherapy be made to optimize treatment for individual patients? Our team is attempting to answer these questions using precision medicine approaches that combine laboratory experiments, computation, and clinical research. The Center is committed to training students and postdocs, promoting junior faculty and ensuring that data and software are reproducible, reliable and publicly accessible.

Funding: The Center for Cancer Systems Pharmacology at Harvard Medical School is an NCI Cancer Systems Biology Center of Excellence funded by grant U54-CA225088 entitled “Systems Pharmacology of Therapeutic and Adverse Responses to Immune Checkpoint and Small Molecule Drugs

News, Events, & Updates

In The News:

Alison Ringel’s and Jefte Drijver’s recent publication in Cell, featuring many CCSP co-authors,

was featured in this NCI blog which includes quotes from PIs Marcia Haigis and Arlene Sharpe.

CSBC Steering Committee Meeting, February 10, 3-4:00 PM

Connection details circulated via email

CCSP Monthly Meeting, February 19, 12-1:30 PM

Featuring the Evans Lab

Connection details circulated via email

Full 2020-2021 meeting schedule

CSBC Steering Committee Meeting, March 10, 3-4:00 PM

Connection details circulated via email

CCSP Monthly Meeting, March 19, 12-1:30 PM

Featuring the Sharpe Lab and the Imaging Platform

Connection details circulated via email

Full 2020-2021 meeting schedule

CSBC Steering Committee Meeting, April 14, 3-4:00 PM

Connection details circulated via email